1995-1999年清华大学生物科学与技术系获学士学位，1999-2004年清华大学生物科学与技术系获博士学位，2004-2007在普林斯顿大学分子生物学系做博士后。主要研究方向为利用蛋白质晶体学和生化、生物物理方法对蛋白质和蛋白质复合体进行结构和功能的研究， 已经发表SCI论文20余篇。

实验室联系人：杨慧蓉
办公室电话：54237294
实验室电话：54237880
Email：xuyh@fudan.edu.cn

代表论文——————————————————————————————

·Xu, Y. *, Chen, Y. *, Zhang, P., Jeffrey, P. D., & Shi, Y. Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-mediated Tau Dephosphorylation. Mol Cell 31, 873-85 (2008). (Cover story)

·Chen, Y., Xu, Y. *, Bao, Q., Xing, Y., Li, Z., Lin, Z., Stock, J. B., Jeffrey, P. D. & Shi, Y. Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Nat Struct Mol Biol 14, 527-34 (2007).

·Xu, Y. *, Xing, Y. *, Chen, Y. *, Chao, Y. *, Lin, Z., Fan, E., Yu, J. W., Strack, S., Jeffrey, P. D. & Shi, Y. Structure of the Protein Phosphatase 2A Holoenzyme. Cell 127, 1239-51 (2006).

·Xing, Y. *, Xu, Y. *, Chen, Y. *, Jeffrey, P. D., Chao, Y., Lin, Z., Li, Z., Strack, S., Stock, J. B. & Shi, Y. Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. Cell 127, 341-53 (2006).

·Xu, Y. *, Liu, Y. *, Lou, Z. *, Qin, L., Li, X., Bai, Z., Pang, H., Tien, P., Gao, G. F. & Rao, Z. Structural basis for coronavirus-mediated membrane fusion. Crystal structure of mouse hepatitis virus spike protein fusion core. J Biol Chem 279, 30514-22 (2004).

·Xu, Y., Lou, Z., Liu, Y., Pang, H., Tien, P., Gao, G. F. & Rao, Z. Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core. J Biol Chem 279, 49414-9 (2004).

* These authors contributed equally to the work