Strategy for the Development of the Institute
Translational medicine is supported by three core scientific platforms: technical service platform, disciplinary development platform, interdisciplinary research platform.
The development of the Institute will be supported through the recruitment of talented researchers to lead large projects and do pioneering first-class research.
Expansion of the Institute will be achieved through the establishment of the State Key Laboratory of Epigenetics.

Research Directions
IBS focuses on the following research directions: Systems biology, Birth Defects and Developmental biology, Molecular mechanisms for Diseases, Innovative Drugs and Structural Biology. This follows the National Medium and Long Term Science and Technology plan and the Shanghai Municipal program for economic and social development.

Faculties and Staff
The IBS faculty includes 7 academicians, 21 full-time PIs, 8 time-sharing PIs, 43 part-time PIs, more than 20 researchers and 20 technicians.
The current research teams are: liver cancer research team, infectious research team, proteomics research team, genomic development analysis and applications research team, stem cell research team, molecular and cellular biology research team, epigenetics research team, structural biology research team and pathology research team.
During the last 5 years, IBS has accomplished a series of important scientific research and funding milestones. The full-time and jointly appointed faculty has successfully applied for state and local scientific research project support; current research project funding exceeds RMB 540 million. IBS has published more than 400 papers in high level academic journals such as Science, Cell, PNAS and JBC including first author papers in Science and Cell.

Core Facilities
The biomedical sciences research base currently consists of 31 large-scale instruments (>$50k) including; Mass Spectrometer, NMR spectrometer, X-Ray Diffractometer, DNA Sequencer, High throughput gene chip system, High throughput genomic analysis system, Laser Capture Microdissection System, Flow Cytometry, Luminescent and Fluorescent Image Analyzer, High-resolution in vivo Imaging System, Typhoon Multifunction Scanner, Laboratory Robots and DNA synthesizers. Through shared core facilities, IBS provides high quality technical support and service for IBS based researchers. A mechanism is also in place whereby external researchers can access shared equipment.

Intellectual Training
The aim of IBS is to provide innovative training for high-level graduate students who can adapt to the interdisciplinary fields between life science and medicine. IBS trains graduate students in the following areas: Proteomics, Chemical Biology, Biochemistry and Molecular Biology, Molecular Pharmacology. All of the research teams recruit post doctoral researchers nationally and internationally.

Great progress in the understanding of human health and disease is being made all the time. However, the gap between basic biological research and its medical application in the clinic remains a serious problem. This emphasizes the importance of the long-term goal of developing an integrated biomedical translational research platform. The state 125, and medium-and-long-term science and technology development plans, provide an opportunity for innovative research projects based on the existing strengths within IBS. This will accelerate the translation of basic biological research into the biomedical arena and make a significant contribution to the health needs of the nation.